In the workplace we've written a pretty extensive suite of command-line programs in Python using the argparse module. It has some nice features to easily define subcommands as well as mandatory positional arguments, different argument multiplicities, etc. While most simple command line apps don't need this kind of functionality, the kinds of apps we are writing at my employer often do.
Anyway, neither of those cases are by any means a major downer, just two things that have been niggling me from time to time.
Somebody mentioned recently that the code that is part of the `go` tool that handles sub-commands maybe should be factored out and added to the stdlib, it should be relatively straightforward. If you are also interested in that I would recommend filling an issue in the tracker and if a few more people find it useful it probably will happen sooner rather than latter.
Anyway, neither of those cases are by any means a major downer, just two things that have been niggling me from time to time.